Open AccessSynthesis of Ibuprofen Using Silica-Supported Preyssler Nanoparticles ( H 14 [Na P 5 W 30 O 110 ]/ SiO 2 )
Author(s) -
Ali Gharib,
Nader Noroozi Pesyan,
Leila Vojdani Fard,
Mina Roshani
Publication year - 2014
Publication title -
organic chemistry international
Language(s) - English
Resource type - Journals
eISSN - 2090-2018
pISSN - 2090-200X
DOI - 10.1155/2014/906801
Subject(s) - reusability , nanoparticle , ibuprofen , hydrolysis , algorithm , computer science , chemical engineering , materials science , nanotechnology , chemistry , organic chemistry , programming language , software , engineering , pharmacology , medicine
This paper describes an alternative and simple procedure for the synthesis of Ibuprofen using Silica-Supported Preyssler Nanoparticles (H14[NaP5W30O110]/SiO2) (SPNPs), as an eco-friendly, inexpensive, and efficient catalyst. High yields, simplicity of operation, and easy work-up procedure are some advantages of this protocol. Silica-Supported Preyssler Nanoparticles (H14[NaP5W30O110]/SiO2) (SPNPs) offer the advantages of a higher hydrolytic and thermal stability. The salient features of Preyssler’s anion are availability, nontoxicity and reusability. We believe this methodology can find usefulness in organic synthesis
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