Open AccessLytic lesion of skull: a rare presentation of chronic granulomatous disease
Author(s) -
Gurinder Kumar
Publication year - 2020
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr-2020-235423
Subject(s) - lytic cycle , medicine , chronic granulomatous disease , skull , lesion , rare disease , presentation (obstetrics) , granulomatous disease , serratia marcescens , pathology , disease , radiology , surgery , immunology , biology , gene , biochemistry , virus , escherichia coli
An 18-month-old boy presented with lytic lesion of skull and recurrent abscesses with Serratia marcescens The extensive work up revealed a gene mutation confirming the diagnosis of chronic granulomatous disease (CGD). This case scenario underscores the importance of exploring the possibility of immunodeficiency if there is a history of recurrent abscesses with atypical organism. The case also demonstrates that CGD can present as lytic lesion of skull.