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mSphere of Influence: the Importance of Metabolism for Pathogen Adaptation to Host-Imposed Stresses
Author(s) -
Jorge Amich
Publication year - 2019
Publication title -
msphere
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.749
H-Index - 39
ISSN - 2379-5042
DOI - 10.1128/msphere.00566-19
Subject(s) - aspergillus fumigatus , biology , pathogen , microbiology and biotechnology , host (biology) , genetics
Jorge Amich studies several aspects of sulfur and nitrogen metabolism in Aspergillus fumigatus , with the ultimate aim of identifying targets for the development of novel antifungals. In this mSphere of Influence article, he reflects on how "Sub-Telomere Directed Gene Expression during Initiation of Invasive Aspergillosis" (A. McDonagh, N. D. Fedorova, J. Crabtree, Y. Yu, S. Kim, et al., PLoS Pathog 4:e1000154, 2008, https://doi.org/10.1371/journal.ppat.1000154) impacted his thinking about in vivo metabolism and how to investigate it.

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