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A method forChlamydia trachomatis restriction fragment length polymorphism (RFLP) analysis and complete sequencing ofomp1 was developed for use on samples collected at home, and results were compared. Genotyping by sequencing was superior to RFLP analysis. Theomp1 gene in 31 clinical strains harbored few mutations compared to the same gene in ATCC reference strains. Follow-up samples obtained during a 24-week period from 31 patients showed recurrence with the same genotype in five cases and a new genotype in one case.

High-Resolution Genotyping of Chlamydia trachomatis from Recurrent Urogenital Infections