Detection of influenza virus neuraminidase-specific antibodies by an enzyme-linked immunosorbent assay | Zendy

M W Khan | Zendy; Marie R. Gallagher | Zendy; Doris J. Bucher | Zendy; Chiara Cerini | Zendy; Edwin D. Kilbourne | Zendy

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Detection of influenza virus neuraminidase-specific antibodies by an enzyme-linked immunosorbent assay

Author(s) -

M W Khan,

Marie R. Gallagher,

Doris J. Bucher,

Chiara Cerini,

Edwin D. Kilbourne

Publication year - 1982

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.16.1.115-122.1982

Subject(s) - neuraminidase , antibody , virology , virus , enzyme , orthomyxoviridae , neuraminidase inhibitor , biology , influenza a virus , immunology , medicine , biochemistry , covid-19 , pathology , disease , infectious disease (medical specialty)

An enzyme-linked immunosorbent assay was developed for the titration of antibodies in human sera to influenza virus neuraminidase, employing partially purified N1 neuraminidase. Specificity of the test was demonstrated, and the test was more sensitive than either the conventional neuraminidase inhibition or plaque size reduction tests in detecting anti-neuraminidase antibody.

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