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The uptake of a specific14 C-amino acid by the heterotrophic microorganisms in the epilimnion of an eutrophic lake was influenced by the presence of other amino acids. The effect of unlabeled serine on14 C-glycine uptake was shown to be caused by competitive inhibition, which changed the interpretation of the kinetic parameters, the turnover time,Tt , and the sum of a transport constant, (Kt + (Sn ), and the natural substrate concentration. The maximum velocity of uptake,V max , is unaffected by the competitive inhibition.

Competitive Inhibition for Amino Acid Uptake by the Indigenous Microflora of Upper Klamath Lake