Open AccessDevelopment of a Serum-Based Taqman Real-Time PCR Assay for Diagnosis of Invasive Aspergillosis
Author(s) -
S. Challier,
Stéphane Boyer,
Éric Abachin,
Patrick Berche
Publication year - 2004
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.42.2.844-846.2004
Subject(s) - taqman , aspergillosis , aspergillus fumigatus , aspergillus , real time polymerase chain reaction , biology , virology , microbiology and biotechnology , polymerase chain reaction , immunology , gene , biochemistry
We compared an Aspergillus fumigatus-specific Taqman real-time PCR assay for the diagnosis of invasive aspergillosis (IA) with the enzyme-linked immunosorbent assay Platelia Aspergillus method. Patients with proven or probable IA had positive results with at least one of the two methods. The PCR method seems to be more specific, and a combination of the two should improve the diagnosis of IA.
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