Comparison of three rapid methods for detection of antibodies to streptolysin O and DNase B | Zendy

C L Hostetler | Zendy; Kjell Sawyer | Zendy; Irving Nachamkin | Zendy

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Comparison of three rapid methods for detection of antibodies to streptolysin O and DNase B

Author(s) -

C L Hostetler,

Kjell Sawyer,

Irving Nachamkin

Publication year - 1988

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.26.7.1406-1408.1988

Subject(s) - streptolysin , antibody , microbiology and biotechnology , bacterial protein , chemistry , medicine , biology , immunology , bacteria , genetics

Three commercial systems were compared for ability to detect antibodies to streptolysin O (ASO) and DNase B (ADB). Streptozyme (Wampole Laboratories, Cranbury, N.J.) exhibited high sensitivity (100%) for detecting ASO but low sensitivity for ADB (22.2%). The LeapStrep (Organon Teknika, Malvern, Pa.) and Check-Spectra (Diagnostic Technology, Hauppauge, N.Y.) tests had low sensitivities for detecting ASO (35.3 and 21.4%, respectively) and ADB (22.2 and 33.3%, respectively).

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