Open AccessA Stewardship Approach To Optimize Antimicrobial Therapy through Use of a Rapid Microarray Assay on Blood Cultures Positive for Gram-Negative Bacteria
Author(s) -
Conner Sothoron,
Jason Ferreira,
Nilmarie Guzman,
Petra Aldridge,
Yvette S. McCarter,
Christopher Jankowski
Publication year - 2015
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.02161-15
Subject(s) - antimicrobial stewardship , bacteremia , antimicrobial , blood culture , microarray , microbiology and biotechnology , gram negative bacteria , bacteria , gram positive bacteria , medicine , gram , biology , antibiotics , escherichia coli , antibiotic resistance , gene expression , biochemistry , genetics , gene
A Gram-negative (GN) blood culture microarray assay with an antimicrobial stewardship program (ASP) intervention was evaluated in 126 patients with GN bacteremia. The median time to optimal therapy was shorter in the postintervention group than in the preintervention group (49.3 h versus 38.5 h, respectively;P = 0.0199). ASP can utilize microarray technology to decrease the time to optimal antimicrobial therapy.
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