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Amniotic membrane transplantation for ligneous conjunctivitis in a doberman
Author(s) -
O'Leary Louise,
Specht Andrew,
Isaza Natalie,
Kallberg Maria,
Barrie Kathleen,
Cottrell Deborah,
Plummer Caryn
Publication year - 2018
Publication title -
veterinary ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.594
H-Index - 50
eISSN - 1463-5224
pISSN - 1463-5216
DOI - 10.1111/vop.12559
Subject(s) - transplantation , medicine , cornea , corneal opacity , pathology , ophthalmology , surgery
Abstract An approximately 2‐year‐old female Doberman Pinscher was referred for the evaluation of bilateral, chronic proliferative conjunctivitis. Ophthalmic examination revealed bilateral thick, opaque pseudomembranes originating from the conjunctivae that prevented visualization of the cornea and interior structures of the eye. Histopathological findings of biopsies of the pseudomembranes were consistent with ligneous conjunctivitis. Serum plasminogen activity levels were within the normal range. Treatment with topical and systemic anti‐inflammatory and immunosuppressive drugs did not improve the conjunctival lesions. The pseudomembranes were surgically excised, and the conjunctival surfaces were reconstructed with amniotic membrane. At final re‐examination two years postsurgery, there was no evidence of recurrence of the pseudomembranes. To the authors’ knowledge, this is the first reported case of the successful treatment of canine ligneous conjunctivitis with amniotic membrane transplantation.