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Paraneoplastic hypertrophic osteopathy in 30 dogs
Author(s) -
Withers S. S.,
Johnson E. G.,
Culp W. T. N.,
Rodriguez C. O.,
Skorupski K. A.,
Rebhun R. B.
Publication year - 2015
Publication title -
veterinary and comparative oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 34
eISSN - 1476-5829
pISSN - 1476-5810
DOI - 10.1111/vco.12026
Subject(s) - medicine , neutrophilia , lameness , lethargy , physical examination , pathology , dermatology , surgery
Abstract Paraneoplastic hypertrophic osteopathy ( pHO ) is known to occur in both canine and human cancer patients. While the pathology of pHO is well‐described in the dog, very little information exists regarding the true clinical presentation of dogs affected with pHO . The primary objective of this study was to provide a more comprehensive clinical picture of pHO . To this end, we retrospectively identified 30 dogs and recorded data regarding presenting complaints and physical examination ( PE ) findings on the date of pHO diagnosis. As a secondary objective, any blood test results were also collected from the computerized records. The most common clinical signs included leg swelling, ocular discharge and/or episcleral injection, lameness, and lethargy. The most common haematological and serum biochemical abnormalities included anaemia, neutrophilia and elevated alkaline phosphatase. In addition to presenting a more detailed clinical description of pHO in the dog, these data support the previously described haematological, serum biochemical and PE abnormalities published in individual case reports.