Review of cobalamin status and disorders of cobalamin metabolism in dogs | Zendy

Kather Stefanie | Zendy; Grützner Niels | Zendy; Kook Peter H. | Zendy; Dengler Franziska | Zendy; Heilmann Romy M. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Review of cobalamin status and disorders of cobalamin metabolism in dogs

Author(s) -

Kather Stefanie,

Grützner Niels,

Kook Peter H.,

Dengler Franziska,

Heilmann Romy M.

Publication year - 2019

Publication title -

journal of veterinary internal medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.356

H-Index - 103

eISSN - 1939-1676

pISSN - 0891-6640

DOI - 10.1111/jvim.15638

Subject(s) - cobalamin , medicine , vitamin b12 , clinical significance , physiology , gastroenterology , endocrinology

Disorders of cobalamin (vitamin B 12 ) metabolism are increasingly recognized in small animal medicine and have a variety of causes ranging from chronic gastrointestinal disease to hereditary defects in cobalamin metabolism. Measurement of serum cobalamin concentration, often in combination with serum folate concentration, is routinely performed as a diagnostic test in clinical practice. While the detection of hypocobalaminemia has therapeutic implications, interpretation of cobalamin status in dogs can be challenging. The aim of this review is to define hypocobalaminemia and cobalamin deficiency, normocobalaminemia, and hypercobalaminemia in dogs, describe known cobalamin deficiency states, breed predispositions in dogs, discuss the different biomarkers of importance for evaluating cobalamin status in dogs, and discuss the management of dogs with hypocobalaminemia.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research