Open AccessInfluence of Food Patterns on Endothelial Biomarkers: A Systematic Review
Author(s) -
Defagó María Daniela,
Elorriaga Natalia,
Irazola Vilma Edith,
Rubinstein Adolfo Luis
Publication year - 2014
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/jch.12431
Subject(s) - medicine , observational study , systematic review , medline , environmental health , gerontology , bioinformatics , biochemistry , biology
The purpose of this study was to conduct a systematic review on the association of food patterns ( FP s) and endothelial biomarkers. An electronic literature search from 1990 to 2012 was conducted and reference lists and experts were consulted. Studies without dietary intervention and without language restrictions were considered. Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines were employed. Methodological quality was assessed by Strengthening the Reporting of Observational Studies in Epidemiology guidelines. A total of 546 references were identified, of which 8 were finally included. Several FP s were identified. Healthy FP s (abundant in fruits and vegetables) had a beneficial impact on endothelial function as estimated by circulating levels of biomarkers such as C‐reactive protein, soluble intercellular adhesion molecule 1, soluble vascular adhesion molecule 1, and E‐selectin molecules. Westernized patterns (higher intakes of processed meats, sweets, fried foods, and refined grains) were positively associated with inflammation molecules and atherogenic promoters. The study of FP s in relation to endothelial function contributes to the development of dietary recommendations for improved cardiovascular health and therefore a better lifestyle.