Open AccessThe role of skin and subcutaneous tissues in Dupuytren's contracture: an electron microscopic observation
Author(s) -
Chen Wu,
Zhou Hao,
Pan Zhijun,
Chen Jiansong,
Wang Li
Publication year - 2009
Publication title -
orthopaedic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 23
eISSN - 1757-7861
pISSN - 1757-7853
DOI - 10.1111/j.1757-7861.2009.00028.x
Subject(s) - contracture , medicine , dupuytren's contracture , subcutaneous tissue , skin grafting , fascia , surgery , soft tissue , deep fascia , fasciotomy , dermatology , pathology , clinical trial
Objective: To determine the relationship between the overlying tissues and recurrence of Dupuytren's contracture. Methods: Forty‐three patients (68 hands) who accepted surgical treatment were divided into two groups according to treatment methods: partial fasciectomy or dermofasciectomy and full‐thickness skin graft. Diseased palmar fascia, subcutaneous tissues and skin obtained during surgery were then assessed by electron microscopy. Results: All patients were followed up. None of the hands which accepted dermofasciectomy and full‐thickness skin grafting recurred, while 46.4% of the hands which accepted partial fasciectomy recurred. Under electron microscopic observation, myofibroblasts were found in the skin and subcutaneous tissues. Conclusion: The overlying tissues play an important role in Dupuytren's contracture, which may be a reason for recurrence of this condition after surgical treatment.