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Retinal ischemia in radiation retinopathies: radiobiological concepts and clinical spectrum
Author(s) -
Matet Alexandre
Publication year - 2019
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2019.8042
Subject(s) - retinal , medicine , retina , ischemia , ophthalmology , glaucoma , neuroscience , biology
Eyes irradiated for intraocular malignancies often develop irreversible retinopathy due largely to vascular damage leading to retinal ischemia. In most advanced cases, this severe process leads to refractroy neovascular glaucoma. We will provide an overview of current biological understanding of radiation‐induced retinal vascular damage, in connection with the clinical manifestations observed in irradiated eyes.