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The epithelial‐stromal TGFBI corneal dystrophies
Author(s) -
Lisch W.
Publication year - 2015
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2015.0054
Subject(s) - tgfbi , stromal cell , pathology , medicine , pathological , corneal dystrophy , cornea , ophthalmology , transforming growth factor
Summary Purpose To correct the IC 3D classification system from 2008. Methods To examine the corneal specimens of 54 patients with lattice, granular 1 and 2, Reis‐Bücklers, and Thiel‐Behnke who underwent unilateral penetrating keratoplasty. Results All specimens showed epithelial and stromal pathological deposits by staining with HE and Congo red, and distinct alterations of Bowman's layer. Discussion The 5 TGFBI dystrophies are to classify from the clinical, genetic, but also from the histopathological aspect as “Epithelial‐stromal TGFBI corneal dystrophies.”