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VEGF Trap‐Eye: features of the molecule
Author(s) -
TADAYONI R
Publication year - 2012
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2012.4511.x
Subject(s) - vegf receptors , trap (plumbing) , dosing , mechanism (biology) , vascular endothelial growth factor a , medicine , cancer research , vascular endothelial growth factor , chemistry , pharmacology , geography , philosophy , epistemology , meteorology
The role of the vascular endothelial growth factors in neovascular AMD and the features of the VEGF Trap‐Eye molecule are presented including binding mechanism, affinity, and predicted biologic activities that support the rationale for every‐other‐month dosing.