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GLUCOSE, PYRUVATE, L‐LACTATE, AND CITRATE CONCENTRATIONS IN THE AQUEOUS HUMOUR OF FASTING RABBITS IN RELATION TO AGE
Author(s) -
LAURSEN A. BRUUN,
LORENTZEN S. E.
Publication year - 1975
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1975.tb01774.x
Subject(s) - medicine , endocrinology , aqueous humour , chemistry , metabolism , carbohydrate metabolism , glycolysis , biology , aqueous humor , ophthalmology
Results are reported of determinations of glucose, pyruvate, 1‐lactate and citrate concentrations in aqueous humour from 42 fasting albino rabbits aged from 8 months to 9 years. The glucose concentrations decreased significantly with increasing age. The pyruvate and 1‐lactate concentrations, as well as the ratios of l‐lactate/pyruvate did not change significantly with age. However, the pyruvate concentrations were higher and the l‐lactate/pyruvate ratios were lower in the 2‐year‐old rabbits than in the others. The citrate concentrations were found to rise with increasing age. Because of wide ranges of variation between individuals of the same age groups, the parameters in question have limited value in the evaluation of the energy metabolism of the anterior eye segment.