Hepatobiliary disorders and complications of inflammatory bowel disease | Zendy

VENKATESH Preethi GK | Zendy; NAVANEETHAN Udayakumar | Zendy; SHEN Bo | Zendy

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Hepatobiliary disorders and complications of inflammatory bowel disease

Author(s) -

VENKATESH Preethi GK,

NAVANEETHAN Udayakumar,

SHEN Bo

Publication year - 2011

Publication title -

journal of digestive diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.684

H-Index - 51

eISSN - 1751-2980

pISSN - 1751-2972

DOI - 10.1111/j.1751-2980.2011.00511.x

Subject(s) - medicine , inflammatory bowel disease , gastroenterology , inflammatory bowel diseases , disease , liver disease , pathophysiology , ulcerative colitis , primary sclerosing cholangitis

One of typical examples of liver‐gut cross talk is the interaction and impact of inflammatory bowel disease (IBD) and hepatobiliary (HB) abnormalities on each other's disease course. There are several layers of association between IBD and HB diseases: (i) HB diseases and IBD share pathogenetic mechanisms; (ii) HB diseases parallel structural and pathophysiological changes seen with IBD; and (iii) hepatic toxicity is associated with medical therapy for IBD. Interdisciplinary approach, involving gastroenterologists, hepatologists and, in advanced cases, general, colorectal, and liver transplant surgeons, is advocated.

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