Open AccessLeucocyte antibody screening of donors for the prevention of TRALI
Author(s) -
Bux J.
Publication year - 2009
Publication title -
isbt science series
Language(s) - English
Resource type - Journals
eISSN - 1751-2824
pISSN - 1751-2816
DOI - 10.1111/j.1751-2824.2009.01244.x
Subject(s) - antibody , human leukocyte antigen , medicine , immunology , panel reactive antibody , antigen
Antibody‐mediated TRALI reduction strategies include the exclusion of high plasma volume blood components from risk donors or testing of these donors for leucocyte antibodies, i.e. HLA class I, HLA class II, and HNA antibodies. Recommendations for the detection of leucocyte antibodies have been made by the ISBT Working Party on Granulocyte Immunobiology.