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ANALYTICAL MODELING FOR THE OPTICAL PROPERTIES OF THE SKIN WITH IN VITRO AND IN VIVO APPLICATIONS
Author(s) -
Wan San,
Anderson R. Rox,
Parrish John A.
Publication year - 1981
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1981.tb09030.x
Subject(s) - in vivo , in vitro , chemistry , materials science , biology , microbiology and biotechnology , biochemistry
— Analytical modeling that interrelates the optical properties of multilayered structures is applied to the skin. The mathematical approach is based on relations of diffuse reflectance and transmittance of a multilayered system and the diffuse reflectance and transmittance of each component layer. The formula can also be derived from the Kubelka–Munk theory of radiation transfer. Using both collimated and diffuse incident irradiance, the applicability of the model to human epidermis over the UV and visible region has been verified. The model has been applied to calculate the absorption and scattering coefficients of human epidermis in vitro , and to estimate the epidermal transmittance under simulated in vivo condition.