Open Access40‐YEAR OLD FEMALE WITH A SELLAR MASS
Author(s) -
Huang Yong,
Quan Juan,
Su Hong,
Hu Haixia,
Wang Feng
Publication year - 2012
Publication title -
brain pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.986
H-Index - 132
eISSN - 1750-3639
pISSN - 1015-6305
DOI - 10.1111/j.1750-3639.2012.00641.x
Subject(s) - glial fibrillary acidic protein , pathology , immunohistochemistry , sella turcica , stain , staining , neoplasm , pituitary tumors , biology , medicine , anatomy
Pituicytoma is a rare, low-grade neoplasm that originates in the neurohypophysis of the pituitary gland. We report the clinicopathologic features of a pituicytoma arising in a 40-year-old female who presented with menstrual disorder for 2 months, clinically suggestive of a pituitary microadenoma. The tumor was marked by a proliferation of elongated cells arranged in bundles and interlacing fascicles. The tumor demonstrated positive staining with S-100 protein and patchy staining for glial fibrillary acid protein and Epithelial Membrane Antigen. The tumor did not stain with antibodies to Progesterone receptor and Neu-n. An MIB-1 labeling was lower than 1%. The tumor was subtotally resected and didn’t recur after the initial surgery.