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Engineered arterial models to correlate blood flow to tissue biological response
Author(s) -
Martorell Jordi,
Santomá Pablo,
Molins José J.,
GarcíaGranada Andrés A.,
Bea José A.,
Edelman Elazer R.,
Balcells Mercedes
Publication year - 2012
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2012.06518.x
Subject(s) - blood flow , intensive care medicine , medicine , computer science , bioinformatics , cardiology , computational biology , data science , biology
This paper reviews how biomedical engineers, in collaboration with physicians, biologists, chemists, physicists, and mathematicians, have developed models to explain how the impact of vascular interventions on blood flow predicts subsequent vascular repair. These models have become increasingly sophisticated and precise, propelling us toward optimization of cardiovascular therapeutics in general and personalizing treatments for patients with cardiovascular disease.