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Identification of Boar Testis as a Source and Target Tissue of Relaxin
Author(s) -
Kohsaka Tetsuya,
Kato Shinichi,
Qin Si,
Minagawa Itaru,
Yogo Keiichiro,
Kawarasaki Tatsuo,
Sasada Hiroshi
Publication year - 2009
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2008.03809.x
Subject(s) - relaxin , boar , microbiology and biotechnology , receptor , endocrinology , biology , medicine , hormone , chemistry , biochemistry , anatomy , semen
The expression and cellular localization of relaxin and its own receptor, LGR7/RXFP1, were demonstrated in the boar testis, where relaxin was produced by the Leydig cells as 18‐kDa pro‐relaxin and LGR7/RXFP1 was detected in both Leydig cells and seminiferous epithelial cells, suggesting that a functional relaxin–LGR7/RXFP1 hormone–receptor network operates within the boar testis.