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The Relationship between Lewy Body Disease, Parkinson's Disease, and Alzheimer's Disease
Author(s) -
HARDY JOHN
Publication year - 2003
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2003.tb07474.x
Subject(s) - disease , lewy body , dementia with lewy bodies , lewy body disease , parkinson's disease , neuroscience , psychology , dementia , medicine , pathology
A bstract : The nosological relationship between Parkinson's disease, dementing syndromes with Lewy bodies, and Alzheimer's disease has been the subject of continuing debate. Here I argue, on the basis of recent data from families with hereditary versions of these diseases and from transgenic modeling, that these nosological debates are inevitable, impossible to resolve, and a product of the fact that we define diseases as entities rather than processes.