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From Castration‐Induced Apoptosis of Prostatic Epithelium to the Use of Apoptotic Genes in the Treatment of Prostate Cancer
Author(s) -
ZHANG YE,
NAN BICHENG,
YU JIANG,
SNABBOON TITHI,
ANDRIANI FRANCESCA,
MARCELLI MARCO
Publication year - 2002
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2002.tb04110.x
Subject(s) - apoptosis , prostate cancer , prostate , cancer research , gene , androgen , medicine , cancer , epithelium , oncology , biology , pathology , hormone , genetics
A bstract : Current knowledge of the mechanisms regulating androgen‐ablation‐induced apoptosis is reviewed, and our efforts to develop a system in which genes of the apoptotic pathway are used to induce therapeutic apoptosis in experimental models of prostate cancer are described.