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Antiestrogenic Regulation of Transforming Growth Factor Beta Receptors I and II in Human Breast Cancer Cells
Author(s) -
BUCK M.,
FECHT J. VON,
KNABBE C.
Publication year - 2002
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2002.tb04104.x
Subject(s) - receptor , beta (programming language) , transforming growth factor beta , transforming growth factor , transforming growth factor, beta 3 , chemistry , medicine , endocrinology , cancer research , microbiology and biotechnology , growth factor , biology , tgf alpha , computer science , programming language
A bstract : To obtain more information about the interactions between antiestrogens and transforming growth factor beta (TGF‐β) signaling, we analyzed the influence of different types of antiestrogens on the expression of TGF‐β receptors I (TβRI) and II (TβRII). Our results show that antiestrogens selectively induce TβRII but not TβRI mRNA.