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A Case Report of a Successful Monochorionic Diamniotic Twin Pregnancy in a Patient Affected by Sickle Cell Disease Treated With Erythrocytapheresis
Author(s) -
Motta Serena,
Perseghin Paolo,
Consonni Sara,
Regalia Anna L,
Masera Nicoletta
Publication year - 2010
Publication title -
therapeutic apheresis and dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.415
H-Index - 53
eISSN - 1744-9987
pISSN - 1744-9979
DOI - 10.1111/j.1744-9987.2009.00712.x
Subject(s) - medicine , pregnancy , fetal distress , obstetrics , gestation , twin pregnancy , fetus , disease , pediatrics , genetics , biology
We describe a monochorionic diamniotic twin pregnancy in a 28‐year‐old woman with a severe form of sickle cell disease periodically treated with erythrocytapheresis (EA). During this high risk pregnancy, two sessions of EA were performed without complications, and pain control and fetal growth were optimal. Delivery was carried out by emergency cesarean section at 29 +3 weeks' gestation due to initial fetal distress following twin‐to‐twin transfusion. There were no significant complications for the newborn twins and the post‐partum course was regular. The patient underwent a further EA 7 weeks after surgery. Close collaboration between obstetricians and hematologists with careful maternal‐fetal monitoring and prophylactic EA during pregnancy led to a favorable outcome despite a low maternal body weight, a twin pregnancy, and a severe form of sickle cell disease.