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SHORT COMMUNICATION: MOUSE MONOCLONAL ANTIBODY AGAINST Lyt ‐ 1.1 ALLOANTIGEN *
Author(s) -
Pierres M.,
Rebouah J.P.,
Liabeuf A.,
Dosseto M.
Publication year - 1981
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1981.tb01073.x
Subject(s) - biology , congenic , monoclonal antibody , spleen , immunology , immune system , antibody , virology , microbiology and biotechnology , genetics , gene
SUMMARY A cloned hybridoma, producing an IgM kappa antibody, has been derived from a fusion between NSI myeloma cells and spleen cells from BALB/c mice immune to CBA lymphocytes. Its specificity for Lyt‐1.1 alloantigen has been established from (1) the lymphoid tissue distribution restricted to T cells and (2) the reactivity pattern on a panel of thymocytes from standard and Lyt congenic mouse strains.