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Quinolinic acid: neurotoxicity
Author(s) -
Guillemin Gilles J.
Publication year - 2012
Publication title -
the febs journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.981
H-Index - 204
eISSN - 1742-4658
pISSN - 1742-464X
DOI - 10.1111/j.1742-4658.2012.08493.x
Subject(s) - quinolinic acid , neurocognitive , neurotoxicity , schizophrenia (object oriented programming) , pharmacology , medicine , toxicity , psychiatry , biology , cognition , biochemistry , tryptophan , amino acid
This minireview series reviews some of the most recent findings about quinolinic acid’s cellular toxicity and its implications in diseases such as HIV associated neurocognitive disorders, depressive disorders and schizophrenia, and finally therapeutic strategies with drugs able to interfere with quinolinic acid production and/or effects