Premium
Tec family kinases
Author(s) -
Yu Liang,
Smith C. I. Edvard
Publication year - 2011
Publication title -
the febs journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.981
H-Index - 204
eISSN - 1742-4658
pISSN - 1742-464X
DOI - 10.1111/j.1742-4658.2011.08135.x
Subject(s) - tec , kinase , biology , protein serine threonine kinases , microbiology and biotechnology , protein kinase a , physics , ionosphere , astronomy
Tec family kinases (TFKs) are ancient kinases, vital for the development of both mammals and fruit flies. The first TFKs were described 20 years ago, and one of them, BTK, was found to be vital for B‐lymphocyte development. However, during the last five years several seminal discoveries have been made, significantly advancing our understanding of these signal transducers.