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USE OF 99m Tc‐MERCAPTOACETYLTRIGLYCINE TO EVALUATE RENAL FUNCTION IN HORSES
Author(s) -
Woods Philip R.,
Drost Wm. Tod,
Clarke Cyril R.,
Rodebush Carolyn J.
Publication year - 2000
Publication title -
veterinary radiology and ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.541
H-Index - 60
eISSN - 1740-8261
pISSN - 1058-8183
DOI - 10.1111/j.1740-8261.2000.tb00432.x
Subject(s) - medicine , renal function , renal blood flow , blood flow , horse , urology , nuclear medicine , paleontology , biology
Ten healthy horses were injected intravenously with 99m Tc‐MAG3 and the disappearance of radioactivity from the blood was measured. The total body clearance (C1 B ) and elimination half‐life (t 1/2(β) ) were 7.9 ± 1.5 ml/kg/minute and 32.8 ± 4.1 minutes, respectively. The disappearance of 99m Tc‐MAG 3 from the blood of 2 horses with compromised renal function was also measured. The data suggest that 99m Tc‐MAG 3 is a useful and clinically applicable radiopharmaceutical for measurement of effective renal blood flow in the horse.