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Evaluation of a direct fluorescent antibody test for detection of Chlamydia trachomatis in endocervical specimens
Author(s) -
Dereli DENIZ,
Ertem EKIN,
Serter DEMIR,
YÜCe KEMAL
Publication year - 1991
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1699-0463.1991.tb01284.x
Subject(s) - asymptomatic , chlamydia trachomatis , direct fluorescent antibody , chlamydia , medicine , sex organ , gynecology , outpatient clinic , chlamydiales , chlamydiaceae , chlamydial infection , chlamydia trachomatis infection , antibody , immunology , biology , genetics
A total of 160 endocervical specimens collected from 72 symptomatic and 82 asymptomatic women attending a gynecology outpatient clinic were investigated for genital Chlamydia trachomatis infection by the use of tissue culture and DFA test. The infection rate was 42% for symptomatic and 23% for asymptomatic patient groups. The sensitivity rates of the DFA test in the symptomatic and asymptomatic groups were 84% and 75%), while the specificity rates were 89% and 95%, respectively. The DFA test had an overall sensitivity of 80% and specificity of 93%. There was 90% agreement between the two techniques. Therefore, DFA is recommended as an alternative to tissue culture where laboratory facilities are limited and genital chlamydial infections are highly prevalent.