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FETAL ARTERIAL INVOLVEMENT IN BEHCET'S DISEASE: AN ELECTRON MICROSCOPE STUDY
Author(s) -
Clausen JøRgen,
Bierring Franz
Publication year - 1983
Publication title -
acta pathologica microbiologica scandinavica series a :pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0164
DOI - 10.1111/j.1699-0463.1983.tb02737.x
Subject(s) - fetus , hysterotomy , medicine , tunica media , thoracic aorta , pathology , aorta , edema , pregnancy , smooth muscle , biology , genetics
A fetus, 16 weeks old, was removed by hysterotomy from a patient suffering from Behcet's disease. The patient received systemic steroids during pregnancy. Electron microscopy of the fetal thoracic aorta revealed edema of the sub‐endothelial space and of the luminal part of the tunica media, as well as a pronounced rarefaction and disarrangement of the smooth‐muscle cells. Results obtained from two human fetal aortae used as controls suggest that the fetal aortic lesions were caused by the maternal disease and not by the exposure to steroids.