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GROWTH INHIBITORY EFFECT OF MOUSE SERUM ON EUKARYOTIC CELLS IN A MICRO ASSAY
Author(s) -
GUNDERSEN STEIN,
JACOBSEN JORUNN,
FUNDERUD STEINAR
Publication year - 1981
Publication title -
acta pathologica microbiologica scandinavica section c immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-1328
DOI - 10.1111/j.1699-0463.1981.tb02708.x
Subject(s) - inhibitory postsynaptic potential , agar , microbiology and biotechnology , biology , agar plate , cell culture , cell , tissue culture , chemistry , in vitro , biochemistry , endocrinology , bacteria , genetics
Inhibition of cell growth by B 6 D 2 F 1 (C57BI/6 × DBA/2) mouse serum in tissue culture wells confirming previous findings in the soft agar tumour colony assay is reported. The assay was time saving, more sensitive, and the amount of mouse serum used could in each experiment be reduced by 95% In addition non‐neoplastic cells ordinarily not forming colonies in the soft agar assay could be tested. Such cells were less sensitive to the growth inhibitory effect when compared to neoplastic cells.