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CARCINOMA OF THE PARATHYROID GLAND
Author(s) -
HOLCK SUSANNE,
PEDERSEN NIELS TINGGAARD
Publication year - 1981
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1981.tb00224.x
Subject(s) - ultrastructure , pathology , lesion , malignancy , cytoplasm , parathyroid carcinoma , glycogen , mitosis , parathyroid gland , carcinoma , biology , anatomy , medicine , calcium , endocrinology , microbiology and biotechnology , parathyroid hormone
The morphological features of a functional parathyroid carcinoma in a 34‐year‐old female are presented. The case was unique in the high frequency of mitotic figures permitting a tentative diagnosis of malignancy already on frozen sections. The parathyroid nature of the lesion was established ultrastructurally by demonstration of secretory granules, glycogen particles and lipid material within the cytoplasm. Also noteworthy was the presence of annulate lamellae, denoting rapidly growing tissue. Few examples of this lesion are at hand, and ultrastructural studies which provide valuable information regarding the site of origin, have previously been recorded in only 6 publications.