ANEUPLOIDY AS A MARKER FOR CARCINOMA‐IN‐SITU OF THE TESTIS | Zendy

Müller Jørn | Zendy; Skakkebæk Niels E. | Zendy; Lundsteen Claes | Zendy

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ANEUPLOIDY AS A MARKER FOR CARCINOMA‐IN‐SITU OF THE TESTIS

Author(s) -

Müller Jørn,

Skakkebæk Niels E.,

Lundsteen Claes

Publication year - 1981

Publication title -

acta pathologica microbiologica scandinavica section a pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.909

H-Index - 88

eISSN - 1600-0463

pISSN - 0365-4184

DOI - 10.1111/j.1699-0463.1981.tb00190.x

Subject(s) - carcinoma in situ , in situ , aneuploidy , biology , dna , carcinoma , germ , pathology , microbiology and biotechnology , genetics , chemistry , medicine , chromosome , gene , organic chemistry

A microspectrophotometric study of the DNA content of carcinoma‐in‐situ germ cells in the testes of eight infertile men revealed an aneuploid DNA distribution pattern. The results support the assumption that carcinoma‐in‐situ germ cells are of a malignant nature. The findings also indicate that the DNA content can be used to discriminate between carcinoma‐in‐situ germ cells and spermatogonia.

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