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MIGRATION OF HAEMOPOIETIC CELLS FROM THE YOLK SAC TO THE THYMUS AND THE BURSA OF FABRICIUS IN THE CHICK EMBRYO
Author(s) -
Hemmingsson Erik J.,
Alm Gunnar V.
Publication year - 1973
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1973.tb00480.x
Subject(s) - yolk sac , bursa of fabricius , embryo , biology , yolk , anatomy , lymphatic system , andrology , embryonic stem cell , spleen , microbiology and biotechnology , immunology , genetics , medicine , ecology , gene
The haemopoietic cells of the yolk sac wall of 16‐day‐old chick embryos were locally labelled with 3 H‐thymidine in situ. Appropriate controls for the isotope leaking to other parts of the embryo during the local labelling procedure were performed. With autoradiographic technique heavily labelled haemopoietic cells derived from the yolk sac were demonstrated in the thymus and in the bursa of Fabricius 24 hours later. These results directly support the view that the haemopoitic areas of the yolk sac is at least one origin of the lymphoid precursor cells entering the embryonic chick thymus and bursa of Fabricius.