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Prothrombin and intraventricular haemorrhage
Author(s) -
Fellman Vineta
Publication year - 2005
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2005.tb01983.x
Subject(s) - medicine , intraventricular hemorrhage , coagulation , prothrombin complex concentrate , white matter , prothrombin time , pediatrics , intensive care medicine , pregnancy , gestational age , radiology , genetics , warfarin , magnetic resonance imaging , biology , atrial fibrillation
Abstract In the study by Salonvaara et al., low prothrombin activity in preterm infants was associated with intraventricular haemorrhage (IVH). The interesting research question—do preterm infants who develop IVH have underlying coagulation disturbance?—could not be answered in this study. Conclusion: The association needs further investigation. The role of prothrombin in perinatal brain damage in the development of IVH and of white matter damage has to be further elucidated.