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The effect of hexetidine mouthwash on the prevention of plaque and gingival inflammation: a systematic review
Author(s) -
Afennich F,
Slot DE,
Hossainian N,
Van der Weijden GA
Publication year - 2011
Publication title -
international journal of dental hygiene
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.674
H-Index - 38
eISSN - 1601-5037
pISSN - 1601-5029
DOI - 10.1111/j.1601-5037.2010.00478.x
Subject(s) - medicine , gingivitis , chlorhexidine , gingival inflammation , oral hygiene , dentistry , placebo , meta analysis , medline , cochrane library , dental plaque , alternative medicine , pathology , political science , law
To cite this article:
Int J Dent Hygiene9 , 2011; 182–190
DOI: 10.1111/j.1601‐5037.2010.00478.x
Afennich F, Slot DE, Hossainian N, Van der Weijden GA. The effect of hexetidine mouthwash on the prevention of plaque and gingival inflammation: a systematic review. Abstract: Objective: To review the literature concerning hexetidine‐containing mouthwash as a monotherapy or as an adjunct to oral hygiene in the prevention of plaque accumulation and gingival inflammation. Materials and methods: PubMed‐MEDLINE and the Cochrane‐CENTRAL were searched through January 2010 to identify appropriate studies. The primary outcome measurements were plaque accumulation and gingivitis parameters. Results: Independent screening of titles and abstracts of 168 papers resulted in six publications that met the eligibility criteria. Mean values and standard deviations were obtained by data extraction. Descriptive comparisons are presented for hexetidine mouthwash and control mouthwashes (chlorhexidine and placebo). Conclusions: Considering the potential benefits in the light of the observed side effects, hexetidine appears to be a poor alternative to chlorhexidine.