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Identification and Targeting of Costimulation‐Resistant T cells in Renal Transplantation
Author(s) -
Farber Donna L.
Publication year - 2011
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/j.1600-6143.2010.03361.x
Subject(s) - medicine , immunosuppression , immunology , transplantation , cd28 , population , identification (biology) , t cell , blockade , immunity , belatacept , kidney transplantation , immune system , kidney transplant , biology , receptor , environmental health , botany
A study in this issue by Kirk and colleagues identifying a memory T cell population resistant to CD28 costimulation blockade has implications for using costimulation‐based immunosuppression therapies to prevent rejection while maintaining protective immunity. See article by Lo et al on page 22.