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Clobetasol Ameliorates Aphthous Ulceration in Renal Transplant Patients on Sirolimus
Author(s) -
Chuang P.,
Langone A. J.
Publication year - 2007
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/j.1600-6143.2006.01678.x
Subject(s) - medicine , sirolimus , renal transplant , dermatology , urology , transplantation
Aphthous ulceration is a common side effect of sirolimus. These lesions of the oral mucous membranes are often painful and debilitating, leading to either dose reduction or discontinuation of sirolimus in a significant number of patients. We report that the direct application of clobetasol, a high potency topical steroid, led to prompt resolution of the aphthous ulcers that developed in our renal transplant patients on sir‐olimus‐based immunosuppression .