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West Nile Virus Encephalitis in a Kidney Transplant Recipient
Author(s) -
Shepherd James C.,
Subramanian Aruna,
Montgomery Robert A.,
Samaniego Milagros D.,
Gong Gary,
Bergmann Amy,
Blythe David,
Dropulic Lesia
Publication year - 2004
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/j.1600-6143.2004.00410.x
Subject(s) - medicine , west nile virus , encephalitis , virus , virology , pathology , peripheral blood mononuclear cell , immunology , biology , biochemistry , in vitro
We describe a case of West Nile virus encephalitis in a 54‐year‐old kidney transplant recipient. The clinical course was rapid and fatal. Serial CSF samples showed an evolving mononuclear pleiocytosis and serial MRIs showed increasing signs of cytotoxic edema in her basal ganglia. Seroepidemiological testing indicated that the infection was most likely acquired from transfusion of fresh frozen plasma at the time of transplantation.