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Antiphospholipid Antibodies: Method of Detection
Author(s) -
HARRIS E. N.,
PIERANGELI S.
Publication year - 1992
Publication title -
american journal of reproductive immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.071
H-Index - 97
eISSN - 1600-0897
pISSN - 1046-7408
DOI - 10.1111/j.1600-0897.1992.tb00793.x
Subject(s) - lupus anticoagulant , radioimmunoassay , antibody , antiphospholipid syndrome , medicine , immunology , anticoagulant , systemic lupus erythematosus , disease
ABSTRACT: Antiphospholipid antibody, measured by enzyme‐linked immunosorbent assy (ELISA) or by radioimmunoassay, and the lupus anticoagulant, represent similar but different tests. The ELISA is now well standardized. It is at least partly, and possibly primarily, dependent on the presence of a cofactor, β 2 ‐glycoprotein I. Tests for both antiphospholipid antibody by ELISA and lupus anticoagulant should be performed in patients suspected of having this syndrome.