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The effects of immobilization on the quality of Achilles tendon in rats
Author(s) -
Karpakka J.,
Palokangas H.,
Kovanen V.,
Takala T.
Publication year - 1991
Publication title -
scandinavian journal of medicine and science in sports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.575
H-Index - 115
eISSN - 1600-0838
pISSN - 0905-7188
DOI - 10.1111/j.1600-0838.1991.tb00271.x
Subject(s) - pyridinoline , achilles tendon , tendon , hindlimb , soleus muscle , chemistry , calf muscle , endocrinology , medicine , anatomy , skeletal muscle , enzyme , biochemistry , alkaline phosphatase , osteocalcin
Immobilization of an Achilles tendon in a shortened position for 1 and 3 weeks did not change pyridinoline and mature collagen concentrations. Although a significant decrease in the biosynthesis of collagen was observed simultaneously in the soleus muscle of the same hindlimb, these results suggest that the stability of collagen provided by the nonreducible cross‐link, pyridinoline, is not altered during this type of immobilization. The significance of stable cross‐links for the known decrease in tensile strength during immobilization remains open.