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Comparative metabolism of 4‐ 14 C‐progesterone in normal and chronically inflamed human gingival tissue
Author(s) -
Elattar T. M. A.,
Roth G. D.,
Hugoson A.
Publication year - 1973
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1973.tb00746.x
Subject(s) - gingivitis , metabolism , endocrinology , medicine , in vitro , chemistry , dentistry , biochemistry
The In Vitro metabolism of 4‐ 14 C‐progesterone in six normal and eight chronically inflamed gingival tissues has been investigated. The inflamed gingiva has been twice as active as the normal in converting progesterone to 5α and 5β‐pregnandiones, 20α‐dihydroprogesterone, and other unidentified polar compounds. The clinical implications of these findings as related to gingivitis have been discussed.