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Disc electrophorethic pattern of gingival collagen isolated from a patient with palmoplantar hyperkeratosis
Author(s) -
Shoshan Shmuel,
Finkelstein Shifra,
Rosenzweig Kurt A.
Publication year - 1970
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1970.tb00725.x
Subject(s) - collagenase , hyperkeratosis , pathology , medicine , chemistry , enzyme , biochemistry
Acetic acid soluble collagen was extracted from a sample of clinically uninflamed gingiva obtained from a 14 year‐old boy suffering from Papillon‐Lefevre syndrome (PFS). After purification, the collagen was gelatinized and then examined by disc electrophoresis. Collagen extracted from samples of clinically healthy gingiva (NG) and clinically inflamed gingiva (IG) of otherwise healthy young people, was similarly treated. Comparison of the results showed that the disc electrophoretic pattern of PFS gingival collagen differed from that of NG and IG collagen, and that it was reminiscent of, but not identical with that of published electrophoretic patterns of collagens digested by animal collagenases.