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Effect of repeated intake of a sugar free fluoride‐containing chewing gum on acido genicity and microbial composition of dental plaque
Author(s) -
EKSTRAND JAN,
BIRKHED DOWEN,
LINDGREN LARSERIK,
OLIVEBY ANETTE,
EDWARDSSON STIG,
FROSTELL GOURAN
Publication year - 1985
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1985.tb01974.x
Subject(s) - fluoride , saliva , dental plaque , streptococcus mutans , sucrose , chemistry , chewing gum , placebo , sugar , dentistry , food science , sodium fluoride , medicine , bacteria , biochemistry , biology , inorganic chemistry , alternative medicine , pathology , genetics
In a double blind cross‐over study, 20 subjects were given either a sugar free chewing gum containing 0.25 mg fluoride or the same chewing gum without fluoride, eight times a day for 7 days. The pH of 3‐day‐old plaque was determined before and after each experimental period following a 30‐s mouth‐rinse with 10 ml 15% sucrose. The pH‐decrease was significantly less pronounced after using the fluoride gum than after the placebo gum ( P < 0.001). In a second study, 20 subjects participated in a similar study. In this experiment the acid production activity from sucrose in dental plaque in vitro was determined with the aid of a titration method. In addition, the dental plaque wet weight and the total number of cultivable organisms, Streptococcus mutans and lactobacilli, expressed as the number of colonies per mg plaque, were determined. No significant effect was found on any of these parameters after using the fluoride gum compared to the placebo gum. Thus, the results indicate that slightly elevated levels of fluoride in saliva during daytime, achieved by repeated intake of fluoride gums for 7 days, are sufficient to influence the acidogenicity of dental plaque in vivo.