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REVIEW ARTICLE: An updated review of simian betaretrovirus (SRV) in macaque hosts
Author(s) -
Montiel N.A.
Publication year - 2010
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.2010.00412.x
Subject(s) - nonhuman primate , macaque , rhesus macaque , virology , biology , simian , simian immunodeficiency virus , immunosuppression , immunology , evolutionary biology , human immunodeficiency virus (hiv) , virus , neuroscience
This review is an updated summary of nearly 30 years of SRV history and provides new and critical findings of original research accomplished in the last 5 years including, but not limited to, the pathogenetic mechanisms underlying the origin of hematopoietic abnormalities observed in infected hosts and proposed new SRV serotypes. Despite major advances in the understanding and control of SRV disease, much more remains to be learned and SRV continues to be an exciting and attractive primate model for comparative studies of the mechanisms of retroviral immunosuppression.