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Anti‐human gonadotropin antibodies generated during in vitro fertilization (IVF)‐related cycles: Effect on fertility of rhesus macaques
Author(s) -
Iliff Susan A.,
Molskness Theodore A.,
Stouffer Richard L.
Publication year - 1995
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1995.tb00138.x
Subject(s) - in vitro fertilisation , fertility , andrology , human fertilization , antibody , gonadotropin , biology , gynecology , medicine , endocrinology , pregnancy , immunology , hormone , genetics , population , environmental health
Administration of human gonadotropins such as hFSH, hLH, and hCG to rhesus macaques can result in formation of anti‐human gonadotropin antibodies. To determine whether the presence of these antibodies interferes with subsequent fertility, sixteen female rhesus macaques ( Macaca mulatta ) with known antibody levels were bred with male rhesus macaques. The presence of antibodies did not interfere with conception or maintenance of pregnancy. Furthermore, antibody titers did not increase during gestation or following the resolution of pregnancy.